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What are aliquots?
- What is the difference between an aliquot and a derivative?
When a sample is divided into smaller portions, which are similar in characteristics like the parent, they are called aliquots. E.g., a 10 ml blood tube is aliquoted into 10x1 ml tubes. They only differ in quantity. Derivatives are processed outcomes of a parent specimen which differ in characteristics like type and pathological status. E.g., DNA, RNA, plasma, etc. - Is aliquot the lowest level of the specimen, and can’t have any derived specimen from it?
There are no restrictions. Derivatives can be aliquoted and, aliquots can be further processed. - If we have a tissue that will have RNA, DNA, and protein from it. Then the tissue has to be a derivative or parent specimen, right?
The tissue will be a parent specimen. RNA, DNA, Protein will be derivatives of the tissue. - Can aliquot have different information such as tissue specimen review information from their parents?
Yes, additional/different events like tissue specimen review events can be added at the child level.
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