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- What is the difference between an aliquot and
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- derivative?
When a sample is divided into smaller portions which are similar in characteristics like the parent, they are called aliquots. E.g., a 10 ml blood tube is aliquoted into 10x1 ml tubes. They only differ in quantity. Derivatives are
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- processed outcome of a parent specimen which differ in characteristics like type
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- and pathological status
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- . E.g. a DNA, RNA, plasma, etc.
- Is aliquot the lowest level of specimen, and can’t have any derived specimen from it?
No, there is no restrictions, derivatives can be created from aliquot at any level.
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- There are no restrictions. Derivatives can be aliquoted and aliquots can be further processed.
- If we have a tissue which will have RNA, DNA and protein from it. Then the tissue has to be a derivative or parent specimen, right?
Tissue will be parent
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- specimen. RNA, DNA, Protein will be derivatives of the tissue.
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- Can aliquot has different information such as tissue specimen review information from their parents?
Yes, additional/different events like tissue specimen review event can be added at child level.
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