1. What is the difference between aliquot and derivatives?
When When a sample is divided into smaller portions which are similar in characteristics with like the parent, they are called aliquots. They only differ in quantity. Derivatives are children of specimen which differ in characteristics like type(might be DNA from tissue) and pathological status.
2. Is aliquot the lowest level of specimen, and can’t have any derived specimen from it?
No, there is no restrictions, derivatives can be created from aliquot at any level.
3. If we have a tissue which will have RNA, DNA and protein from it. Then the tissue has to be a derivative or parent specimen, right?
Tissue will be parent and RNA, DNA, Protein will be derivatives of tissue.
4. Can aliquot has different information such as tissue specimen review information from their parents?
5. If our final tissue specimen must be able to differentiate between the individual pieces of the tissue generated from the parent specimen, then the final tissue specimen can’t be aliquot, right?Yes, additional/different events like tissue specimen review event can be added at child level.